Welcome Emma to Kruvelab! In the autumn, we were lucky to participate in an interlaboratory trial on non-target screening (NTS) with liquid chromatography high-resolution mass spectrometry (LC/HRMS) alongside other Swedish labs. We were able to test our ability to identify spiked chemicals in blind water samples as well as quantify the tentatively identified chemicals with […]
Tag Archives: interlaboratory comparison
Recently, I attended my first in-person conference, the Nontarget Analysis for Environmental Risk Assessment SETAC Focused Topic Meeting. It was held in Durham, NC, USA from May 22 -26 2022, and it was a very intense week filled with interesting talks, posters, and meetings with other scientists. It was very nice to put a face […]
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The difficulty in quantifying compounds in LC/ESI/HRMS arises from vastly different responsiveness of the compounds. At the same concentration, two compounds may yield very different signals due to the differences in the ionization efficiency of the compounds. The different responsiveness has made semi-quantitative non-targeted screening challenging. Still, research has been increasingly focussing on enabling the semi-quantification […]