Last week from 20th to 21th of May Tartu hosted Eurachem yearly workshop with the topic of “Validation of targeted and non-targeted methods of analysis”. These two days were filled with exciting presentations, insightful discussions and joy of meeting new and old friends and collaboration partners. What is happening in the field of non-targeted analysis? Eurachem […]
Tag Archives: ESI
27
May
May
Today our master’s student Mari Ojakivi submitted her thesis. She studied the reactions between 7 aldehydes and 4 nitrogen bases in charged droplets. For this, she built an in-house built electrospray system to generate the charged droplets. Mostly imines were observed as reaction products, but also amides were found in some reactions. For comparison, the same reactions […]
16
Jan
Jan
Recently a study in Rapid Communications in Mass Spectrometry was published. In this study, we optimized the actual split ratio and make-up flow composition in LC/ESI/MS analysis to increase the signal in radio detector and enhance the sensitivity of electrospray ionization. High methanol content increases electrospray ionization efficiency We studied make-up flow composition with a […]
21
Sep
Sep
From the 9th to the 13th of September MSACL EU 2018 Annual Congress took place in the cosy city of Salzburg, Austria. This conference was designed to mass spectrometry audience mainly focusing on clinical applications. I had the opportunity to participate in this inspiring conference. Moreover, I had the possibility to give a talk. I introduced our studies on […]
22
Aug
Aug
In the recent years, we have made significant progress in ionization efficiency studies. In our previous publications, we have shown that our approach can be applied in both electrospray positive and negative mode (we have recently also enabled comparing the logIE values measured in both ESI modes numerically), that our approach is transferable between different […]
06
Jan
Jan
Charged droplets occur everywhere in the world. They are created by the oceans (known as see spray aerosols), near waterfalls and in thunderstorm clouds. Such droplets are expected to play significant role in environmental processes. Similar droplets are also created in electrospray ionization (ESI) source. Mari Ojakivi joined our group three years ago to conduct […]
01
Nov
Nov
Recently my first single-authored paper became public. It concerns the solvent effect on electrospray ionization efficiency and matrix effect. As we have talked about ionization efficiency and its solvent effects also previously, let’s focus on matrix effects this time. As LC/ESI/MS is the tool for various fields in routine analyses (quality control over pesticides but also mycotoxins in the food we eat, drug monitoring […]
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