Standard-substance-free quantification in LC/ESI/MS is finally here

We have now gathered our knowledge from years of ESI mechanism research and bundled it with data science to provide you with the possibility to quantify analytes in LC/ESI/MS analysis without the use of standard substances.   The availability of standard substances is one of the main limitations in LC/ESI/MS analysis, especially in the fields […]

New project: synthesis in charged droplets

At the end of last year, our group got very happy news from Estonian Research Council, we received the personal research funding team grant to investigate synthesis in charged droplets (project abbreviation SNT). This new and exciting project allowed us to widen our team. In addition to masters student Mari Ojakivi, already working on the topic, Andi […]

Optimization of flow splitting and make‐up flow conditions in liquid chromatography/electrospray ionization mass spectrometry

Recently a study in Rapid Communications in Mass Spectrometry was published. In this study, we optimized the actual split ratio and make-up flow composition in LC/ESI/MS analysis to increase the signal in radio detector and enhance the sensitivity of electrospray ionization. High methanol content increases electrospray ionization efficiency We studied make-up flow composition with a […]

Anneli is in the Power List 2018 of the Analytical Scientist

Yesterday, the Analytical Scientist published the Top 40 Under 40 Power List to celebrate the gifted and successful young scientists in analytical science. I am very happy to be chosen to this list together with 39 outstanding scientists. I am very grateful for all of the people I have collaborated and worked together with; this honour is definitely […]

MSACL EU 5th Annual Congress & Exhibits in Salzburg

From the 9th to the 13th of September MSACL EU 2018 Annual Congress took place in the cosy city of Salzburg, Austria. This conference was designed to mass spectrometry audience mainly focusing on clinical applications.  I had the opportunity to participate in this inspiring conference. Moreover, I had the possibility to give a talk. I introduced our studies on […]

International Mass Spectrometry Conference 2018 in Florence, Italy

From 26 to 31 of August Florence hosted a vast majority of mass spectrometry scientist in the course of 22nd International Mass Spectrometry Conference. Among these were also our group members and we had a chance to present altogether 5 posters at the conference. Our posters can be found here. As is the case for […]

Prediction of ionization efficiencies in biological matrices

In the recent years, we have made significant progress in ionization efficiency studies. In our previous publications, we have shown that our approach can be applied in both electrospray positive and negative mode (we have recently also enabled comparing the logIE values measured in both ESI modes numerically), that our approach is transferable between different […]

Adventures in Greensboro

I am Mari, currently finished a second-year as a master’s student in Kruve Lab. I spent the last semester (Spring 2018) in Greensboro, North-Carolina as an exchange Graduate student in Chemistry. Besides taking classes like every other exchange student, I could also do some fascinating research in Dr Cech Lab. I have always wanted to […]