Prediction of ionization efficiencies in biological matrices

In the recent years, we have made significant progress in ionization efficiency studies. In our previous publications, we have shown that our approach can be applied in both electrospray positive and negative mode (we have recently also enabled comparing the logIE values measured in both ESI modes numerically), that our approach is transferable between different […]

Adventures in Greensboro

I am Mari, currently finished a second-year as a master’s student in Kruve Lab. I spent the last semester (Spring 2018) in Greensboro, North-Carolina as an exchange Graduate student in Chemistry. Besides taking classes like every other exchange student, I could also do some fascinating research in Dr Cech Lab. I have always wanted to […]

European Mass Spectrometry Conference 2018

Last week I had a chance to take part in the European Mass Spectrometry Conference that was hosted by DGMS (German Society for Mass Spectrometry) and SFSM (Frence Society for Mass Spectrometry). Below I share a few key ideas from this nice conference that took place in Saarbrücken over 5 days. The conference was opened […]

p-value that we call statistically significant

In this post I am going to talk about p-value. You can either watch the illustrative video or read my thoughts below. Enjoy!  This week p-value made it to the Science news feed. The whole story started already in the middle of last year, when Bejamine and coworkers published in Nature Human Behaviuor a […]

What can we learn from mass spectrometry about charged droplets?

Charged droplets occur everywhere in the world. They are created by the oceans (known as see spray aerosols), near waterfalls and in thunderstorm clouds. Such droplets are expected to play significant role in environmental processes. Similar droplets are also created in electrospray ionization (ESI) source. Mari Ojakivi joined our group three years ago to conduct […]

Choosing analyses conditions to get matrix effect free?

Recently my first single-authored paper became public. It concerns the solvent effect on electrospray ionization efficiency and matrix effect. As we have talked about ionization efficiency and its solvent effects also previously, let’s focus on matrix effects this time. As LC/ESI/MS is the tool for various fields in routine analyses (quality control over pesticides but also mycotoxins in the food we eat, drug monitoring […]

Defences in our group: Asko Laaniste and Hanno Evard

We are happily back from IMSC in Toronto and a very important celebration in our group has occurred! On the last day of August two PhD theses were defended in our group by Asko Laaniste and Hanno Evard. Asko wrote his thesis on ionization sources. Specifically focusing on the comparison of different sources for pesticides. […]