Today our master’s student Mari Ojakivi submitted her thesis. She studied the reactions between 7 aldehydes and 4 nitrogen bases in charged droplets. For this, she built an in-house built electrospray system to generate the charged droplets. Mostly imines were observed as reaction products, but also amides were found in some reactions. For comparison, the same reactions […]
Category Archives: Research
10
Apr
Apr
We have now gathered our knowledge from years of ESI mechanism research and bundled it with data science to provide you with the possibility to quantify analytes in LC/ESI/MS analysis without the use of standard substances. The availability of standard substances is one of the main limitations in LC/ESI/MS analysis, especially in the fields […]
31
Jan
Jan
At the end of last year, our group got very happy news from Estonian Research Council, we received the personal research funding team grant to investigate synthesis in charged droplets (project abbreviation SNT). This new and exciting project allowed us to widen our team. In addition to masters student Mari Ojakivi, already working on the topic, Andi […]
16
Jan
Jan
Recently a study in Rapid Communications in Mass Spectrometry was published. In this study, we optimized the actual split ratio and make-up flow composition in LC/ESI/MS analysis to increase the signal in radio detector and enhance the sensitivity of electrospray ionization. High methanol content increases electrospray ionization efficiency We studied make-up flow composition with a […]
03
Jan
Jan
The word cloud of IMSC 2018 topics reveals that quantitation and bio-samples are currently highly important topics in the mass spectrometry. What would be a better start for 2019 than to have a look at where we are standing to set the goals for the upcoming year? At the end of 2018, I gave a […]
21
Sep
Sep
From the 9th to the 13th of September MSACL EU 2018 Annual Congress took place in the cosy city of Salzburg, Austria. This conference was designed to mass spectrometry audience mainly focusing on clinical applications. I had the opportunity to participate in this inspiring conference. Moreover, I had the possibility to give a talk. I introduced our studies on […]
05
Sep
Sep
From 26 to 31 of August Florence hosted a vast majority of mass spectrometry scientist in the course of 22nd International Mass Spectrometry Conference. Among these were also our group members and we had a chance to present altogether 5 posters at the conference. Our posters can be found here. As is the case for […]
22
Aug
Aug
In the recent years, we have made significant progress in ionization efficiency studies. In our previous publications, we have shown that our approach can be applied in both electrospray positive and negative mode (we have recently also enabled comparing the logIE values measured in both ESI modes numerically), that our approach is transferable between different […]
31
Jul
Jul
I am Mari, currently finished a second-year as a master’s student in Kruve Lab. I spent the last semester (Spring 2018) in Greensboro, North-Carolina as an exchange Graduate student in Chemistry. Besides taking classes like every other exchange student, I could also do some fascinating research in Dr Cech Lab. I have always wanted to […]
18
Jun
Jun
Firstly, if you have clicked on our website you have probably noticed that we are on a completely new website! This is a result of hard work from our master’s student Mari and her loving husband Kaur! I am from the bottom of my heart grateful to them. You can see that we now have […]